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Exact(24)
In future studies, the research team plans to investigate why some genes' binding sites are conserved over time while others shift.
However, many are based on sequence and overall structural homology [17, 18], consequently often missing similarities when only local binding sites are conserved.
SRY binding sites are conserved among human, mouse and rat.
However, not all binding sites are conserved [29].
These results demonstrate the fact that thresholding-based methods cannot achieve optimal performance since not all functional binding sites are conserved.
Within most HAdV species, both NF I and NF III binding sites are conserved except for species HAdV-E as seen in HAdV-E4 and HAdV-E4 vaccine strain [42], [43] and simian AdV-21 (SAdV-B21), SAdV-E22 through E25 (unpublished observations) which lack the NF I binding site.
Similar(36)
Many of these binding sites were conserved across the two species, suggesting that CHD8 regulates genes that are broadly important for brain development in mammals.
In the case of Irga1 the homology to the exon 1B region of Irga6 continues upstream across the whole region populated by HNF binding sites, while in Irga2 only the distal cluster of HNF binding sites is conserved (Table S1).
The mechanism of replication (DnaA and its binding sites) is conserved throughout the prokaryotic kingdom.
In the case of the 152 aa USP, the ligand binding sites were conserved.
In a bioinformatics study, POU5F1 transcription factor binding sites were conserved among mammalian FZD5 orthologs [ 39].
More suggestions(22)
binding aspartates are conserved
binding determinants are conserved
binding sites are contained
binding sites are preserved
binding sites are provided
binding sites are paired
binding aspartates are conserved
binding sites are extracted
binding sites are assessed
binding determinants are conserved
binding sites are characterized
binding pockets are conserved
binding sites contain conserved
binding sites are identified
binding sites are given
binding sites are shared
binding sites are maintained
binding sites are assumed
binding domains are conserved
binding sites are juxtaposed
binding sites involve conserved
binding sites are located
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