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We validate our computational methods using the same mouse data set as in [12], which consists of 47 promoter sequences (as shown in Table 2), each with a varying number of annotated binding sites from ABS [3] and ORegAnno [5] databases (the annotated binding sites are also listed in Table 2).
Several clusters of binding sites are also predicted for TFs that are important for mesoderm development (Figure 6).
Similarly, zero binding sites is by far the most frequent case among the MAP number of binding sites (Figure 14 (b)) and the expected number of binding sites are also heavily biased towards small values (Figure 14 (c)).
Relevant transcription factor binding sites are also shown.
DNA structures and cluster binding sites are also controlled by complementary strands.
This kind of binding sites are also called a spaced dyad.
Similar(29)
Moreover, three additional SNPs associated with three transcription binding sites were also identified, which might explain the differential response of Os04g27430 during the anti-feeding test.
Saturation analysis showed that the Bmax of [3H]citalopram binding sites was also significantly lower in the pups prenatally treated with cocaine than in those prenatally treated with saline.
Highly efficient and specific displacements of both ligands from their endogenous mitochondrial binding sites were also demonstrated (data not shown).
Hence, we concluded that, similar to the Atf1, major Pcr1 promoter binding sites were also present before H2O2 treatment.
STAT binding sites were also found with great frequency, again of interest because STAT3 has also been shown to be an important regulator of genes involved in vasculogenesis [25], [26].
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