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Each streptavidin molecule can provide four biotin binding sites, and the streptavidin layer was then ready to bind with the biotinylated RNA aptamers.
(A) Sequences of the CTGF 3′-UTR containing the miR-26a and miR-30c binding sites and the Snail1 3′-UTR conthening the miR-30c binding site.
The structure and confirmation of zinc binding sites and the distinction between catalytic, regulatory and structural ones in several enzymes were delineated and generalization of the related coordination chemistry theorized in an entity called the entatic state.
The number of binding sites and the association binding constants as well as the thermodynamic parameters of Pd II) complex were calculated at both temperatures.
The most significant amino acid residues at binding sites and the requirement for features of substituents were applied to direct design of new inhibitors.
However, aspects such as coupling stoichiometry, molecular properties of binding sites and the nature of conformational changes remain unresolved or the centre of considerable controversy.
In this review, we summarize the common binding modes of Aurora-A kinase inhibitors, the hot spot residues in the binding sites and the privileged inhibitor structures.
The detection mechanism was based on nano-scale transduction of the detection of the localized binding event between the functional binding sites and the chemical species of interest.
Solution pH influences both the carbon surface dye binding sites and the dye chemistry in water.
The binding constants, binding sites and the corresponding thermodynamic parameters (ΔH, ΔG and ΔS) were calculated.
To elucidate the influence of (a) and (b), we compared protonation/tautomerization states of the binding sites and the molecules and quantified the differences.
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