Sentence examples for binding sites and potential from inspiring English sources
Binding free energies of probes that bind strongly to the RNA at the predicted binding sites and potential alternative binding sites were calculated at 4, 22, and 37 °C using the nearest neighbor model and 2′- O-methyl RNA/RNA parameters with bonuses for LNA modifications (37− 40).
Recently, certain GABA subtype A (GABAA) receptor subtypes emerged as high-affinity GHB binding sites and potential physiological mediators of GHB effects.
From a survey of microRNA target prediction programs including MiRanda, TargetScan, and Mirtarget, Sox6 emerged as an attractive candidate, given three potential miR-499 binding sites and potential roles for Sox6 in muscle and heart [36] [38], [45], [46].
Much remains to be discovered, however, of the rules for predicting binding sites and potential therapeutics.
An amended gene sequence encoding Nluc was designed by optimizing codon usage for expression in mammalian cells (www.kazusa.or.jp/codon), removing potentially strong mRNA secondary structure (http://mfold.rna.albany.edu), and removing consensus promoter sequences, other transcription factor binding sites, and potential eukaryotic mRNA splice sites.
First, BEAN2.0 takes the sequence composition of the middle and C-terminal into account with the purpose of incorporating more possible type-III secretion-related information, such as chaperone-binding sites and potential C-terminal secretion signal.
Based on the facts that most PI3K inhibitors apparently bind to the ATP-binding site of p110, the catalytic subunit of PI3K [15], and that S9 is a pan-inhibitor for PIKK family members, molecular docking approach was performed to predict their potential binding sites and possible binding mode between S9 and p110α (Figure 2E).
A search for local sequence features that might account for site-specific differences in PRE behavior revealed different numbers of the motifs GTGTG, GAGAG (potential GAF binding sites) and GCCAT (potential PHO binding sites) (Table 1).
The identification of NAC and YABBY transcription factor binding sites and the potential genes regulated by these transcription factors will advance our understanding of gene regulation during legume development.
In silico analysis of the Aven promoter region, using Matbase from Genomatix (http://www.genomatix.de), enabled the identification of a progesterone receptor-binding site and potential CDE/CHR cell-dependent element, which is known to regulate cell cycle-dependent transcription (Supplementary Figure S1c).
