Sentence examples for binding sites and not from inspiring English sources

Our ERα regulatory network model, however, is not able to identify RAR targets, as the ChIP-chip experiments were only performed for ERα binding sites and not RAR.

These data indicate the importance of conserved nucleotide sequences of miR-1322 binding sites and not only the amino acid sequence corresponding to oligopeptides of the encoded protein.

Moreover, the number of slack variables (ξ b) in MI-1 SVM is equal to the number of binding sites and not the number of training examples, as in the vanilla SVM and the mi-SVM.

Obviously, this hybrid model could be possible only if a certain type of sequences is found to be enriched at all DCC binding sites and not only at the high affinity ones.

In fact, several genes in the DAL gene cluster are induced by the orc2-1 mutandon, atd at least two of these genes are also induced by deletion of nearby ORC binding sites, and not by the orc2-1 mutation when these binding sites are deleted from orc2-1 cells [ 5].

These results suggest that plinabulin binds in the boundary region between α- and β-tubulin near the colchicine binding site, and not inside the colchicine binding cavity.

In theory, this can be due (i) to low sensitivity of the HCVpp neutralization assay [37] or, (ii) to the role played by residues located outside the CD81 binding site and not tested in the mutants panel, but possibly important for the neutralizing activity of e20 against genotype 5 [44].

Replication of the singly M250V substituted HBV was 7-fold hypersensitive to LVD in culture (wildtype HBV LVD EC50 = 794 nM, M250V HBV LVD EC50 = 116 nM), suggesting the M250 changes affected the dNTP binding site and not just elongation of the growing DNA.

These results together with the thermal shifts and STD NMR spectroscopy experiments provide evidence that the fragments are behaving competitively with the FHTA ligand for the protein binding site, and not behaving as general denaturants.

Even so, this enrichment is limited to the 4 bp YY1 core binding site and not the complete 10 bp motif which we used to calculate YY1 density in OLFR genes.

The α7/5-HT3 chimera, when expressed heterologously in a human epithelial cell line, SH-EP1, robustly expressed α-bungarotoxin binding sites as homooligomers while the α3/5-HT3 did not produce epibatidine (non-selective ligand) binding sites, and did not interfere the α7/5-HT3 phenotype, upon co-expression.