Sentence examples for binding site would require from inspiring English sources

A systematic study of the binding epitope through single amino acid replacements can test the functional importance of individual residues, but a complete analysis of even a small binding site would require an impractically large number of mutants.

A pre-formed binding site would require a chitin oligomer to slide along the two LysM domain binding sites, which is practically impossible.

A transcriptional regulatory process that involves either antiparallel binding of two copies of a transcription factor, or binding of a homodimeric factor with antiparallel binding sites, would require an inverted repeat-binding site.

Similarly, any transcriptional regulatory activity that requires either antiparallel binding of two copies of a transcription factor, or binding of a homodimeric factor with antiparallel binding sites, would require an IR.

Both possible sites would require approval from the California Coastal Commission.

A protein binding site would be an attractive hypothesis.

In vivo, however, most such binding sites would be non-functional, perhaps because the chromatin conformation around the sites precludes access to the DNA (Segal et al., 2006) or because the target factors require the cooperative binding of additional factors nearby to properly exert their regulatory function (Ravasi et al., 2010).

Using the same amplifying strategy as before the H2-binding site would also be present offering a second binding site.

Clearly, hormone binding would require a conformational change in CL1 to expose the putative hormone binding site.

The validation of a (putative) regulatory element as the binding site for these TFs would require extensive further experimentation.

This method is impossible to apply to the study of slow-onset inhibition of DCS at the C-terminal d-Ala binding site of MtDdl, as preincubation would require both ATP and d-Ala (the substrate for the N-terminal site), generating a kinetically competent enzyme complex in the process.