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Also, the affinity of the molecule with haemoglobin binding site would determine the degree of the active anti-sickling agents.
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It would be interesting to determine whether some of these anti-EGFR mAbs in our panel, which are directed against epitopes distinct from the ICR62 binding site, would be effective in inhibiting the growth of DiFi62 cells.
A protein binding site would be an attractive hypothesis.
To ensure that possible polymorphisms in the primer or probe binding sites would not influence the amplification of the PCR products, we determined the amplification efficiencies for all transcripts and mouse strains shown in Fig. 5.
We reasoned that the use of two very different approaches to determine the genome-wide HLH-1 binding sites would allow us to cross validate the data from each while exploring techniques that could be used to overcome limitations that will be commonly encountered in the study of transcription factor binding sites by ChIP.
The binding of Sam68 to its two binding sites would be necessary for efficient complex formation, involving the recruitment of U2AF, and so could determine the overall level of v5 exon inclusion.
The binding sites would not only reveal mRNA targets but would show GQ motif consensus if that's really the in vivo binding site for Aven.
Using the same amplifying strategy as before the H2-binding site would also be present offering a second binding site.
We first determined the membrane topology of Malectin because only the luminal orientation of the protein's carbohydrate binding-site would be consistent with a role of this protein in ER quality control.
Koel, B. F. et al. Substitutions near the receptor binding site determine major antigenic change during influenza virus evolution.
We used ENCODE transcription factor binding site data to determine whether NF-κB and AP-1 binding sites associated with the EMT-GCs via binding sites at enhancers.
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