Sentence examples for binding site within the from inspiring English sources
CadC is a transcriptional regulator, which binds after activation to its binding site within the cadBA promoter.
Na+ ions work as negative allosteric modulators for many class A GPCRs31,32, and recent crystal structures have revealed the conserved binding site within the transmembrane bundle33,34,35,36.
Gel shift experiments using extracts obtained from PCCl3 cells demonstrated the existence of at least one functional Sp1 binding site within the THOX1 DUOXA1 promoter.
Three fluoroionophores (2a c) were designed as the intramolecular charge transfer (CT) dual fluorescent sensors for metal cations with metal binding site within the electron acceptor.
Electrophysiological measurements show that drug-resistant mutations have minimal effects on M2's specific activity, and suggest that resistance is achieved by altering a binding site within the pore rather than a less direct allosteric mechanism.
However, nothing is known about whether such compounds are themselves transported by Pgp, or whether they affect Pgp expression as well as its activity, or about the location of their binding site within the protein.
This is consistent with the idea that CadC binds to its chromosomal-binding site within the cadBA promoter or diffuses randomly within the membrane.
To further confirm this model, we deleted the native CadC-binding site within the chromosome and inserted a new one at the chromosome near the terminus.
However, extensive attempts to identify potential cation-binding site within the channel pore with crystals grown in various conditions, containing K+, or Rb+, or Cs+, were unsuccessful so far (for details, see Supplementary Table 2).
In this communication, I will discuss the pros and cons of targeting the PBD in comparison to those of targeting the ATP-binding site within the kinase domain.
Single-base changes in either a 5' exon sequence or a 5' exon-binding site within the IVS disrupt their ability to pair and result in inefficient or inaccurate splicing.
