Sentence examples for binding site within a from inspiring English sources

By doing this extensive modeling study they have developed the first three dimensional visualization of an anesthetic binding site within a clinically relevant protein.

A single E2F binding site within a 100-bp enhancer is necessary and sufficient to direct the correct spatiotemporal program of G1-S-regulated PCNA expression during development.

The MX2 genomic region contains an EN2/PBX binding site within a intronic region (Fig. 6A), and qPCR analysis of WMPY-1 cells treated with EN2 protein revealed a 12-fold12-foldse in transcription stepwise over 4 logs of increasing protein concentration (Fig. 6B).

Each transcription factor binding site within a cis-regulatory module contributes information about when, where, or how much a gene is turned on, and by dissecting the modules driving a given gene, all the inputs governing expression of the gene can be accurately identified.

A6U forms the least stable structure and presents most of the anchor binding site within a terminal loop, defined by an 8 bp stem (ΔG27°C = −8 Kcal mole−1).

Below it will be shown that this model suffers from a bias towards regulation of genes with a large part of their upstream sequence evolutionarily conserved, simply because it is more likely to predict a binding site within a longer sequence stretch than within a short one.

Genes with a binding site within an interval from −2 kb to +1 kb around the transcriptional start sites were determined as bound.

Indeed, a binding site within an intensively transcribed region is unlikely effective due to interference of the factor with RNA polymerases.

For each binding instance, RNAMotifModeler defines a score that evaluates the consensus binding site within an optimal structural context, and aims at searching for an optimal RNA sequence-structural consensus for an RNA binding protein.

Recently, Murray and colleagues identified a common functional variant in an AP-2α binding site within an IRF6 enhancer that showed highly significant linkage disequilibrium with isolated cleft lip, but not with cleft lip and palate or isolated CLP (46).

Intriguingly, the presence of a miR-148 binding site within an alternatively-spliced exon of DNA (cytosine-5- -methyltransferase cytosine-5- -methyltransferasee differential expression of splicytosine-5- -methyltransferase