Sentence examples for binding site while the from inspiring English sources

Chelerythrine binds flat in the PrgI binding site, while the compound points into the corresponding Bcl-xL binding site partially overlaying helix α4.

Such a monomer or heterodimer might favor a non-canonical CRP binding site, while the homodimer remains its ability to bind to the conventional palindromic motif.

Using both computational and experimental approaches, we provided evidence suggesting that griseofulvin binds to tubulin in two different sites; one site overlaps with the paclitaxel binding site while the second site is located at the αβ intra-dimer interface.

This rigid docking procedure ensured the flexible conformational search for the ligand within the binding site while the protein remained in its original conformation.

Most promoters contain one binding site, while the promoters of hsa-mir-21 and hsa-mir-92b have two STAT1 target sites, and a microRNA cluster, hsa-mir-193b and hsa-mir-365-1 hsa-mir-365-1 hsa-mir-365-1 hsa-mir-365-1

Specifically, the STAT5-mut harbored a point mutation in the STAT5 consensus binding site, while the −298/22κB mut had three base substitutions in the RELA/p50 consensus binding site.

Several residues, e.g., E68, N142, T431, and N267, facilitate the substrate's initial displacement from the binding site, while along the remainder of the exit pathway, the translocation of the substrate is facilitated by the sequential formation and breakage of H-bonds between the substrate and a series of conserved, polar residues lining the pathway.

AutoDock4 determines the conformations of a ligand in the binding site while minimising the total energy of the protein ligand complex, computed according to the following equations (Huey et al, 2007): ΔG refers to the change in free energy of Van der Waals, hydrogen bonding, electrostatic, desolvation, and torsional forces.

The Langmuir isotherm (Langmuir 1916) assumes a surface with homogeneous binding sites, while the Freundlich isotherm (Freundlich 1906) describes multilayer adsorption.

alpha-Adrenergic antagonists, such as phentolamine and phenoxybenzamine, potently compete for the binding sites while the beta-adrenergic antagonist propranolol does not.

In the former one, Fib and biotinylated Fib competed for the immobilized Nb binding sites while the latter configuration involved competition of free Fib in solution and immobilized Fib for binding to a fixed amount of the specific biotinylated Nb.