Sentence examples for binding site which has from inspiring English sources
The S4 binding site, which has been described as the key determinant of substrate specificity, varied markedly between the different caspases.
This may be attributed to the presence of cysteine residue in the epitope binding site which has been shown critical for stabilizing the gp120 core.
ST shares the same amino terminus as LT, but has a distinct carboxy terminus containing a protein phosphatase 2A binding site, which has been shown to be important in other polyomaviruses for virus-induced transformation [ 6].
These include a cation−π interaction between the protonated amine of endogenous ligands and one of several conserved aromatic amino acids in the binding site, which has been demonstrated in all Cys-loop receptors studied to date.
All three SNPs have differential predicted TF binding affinity of distinct TFs, but rs1391720 shows the strongest significance for an Nr2e3 binding site, which has been previously reported to be an upstream regulator of ESR1 in breast cancer [ 43].
When binding to DNA, LysR protein forms a homodimer and targets two specific binding sites, a regulatory binding site, which has the conserved T-N11-A/TTA-N7/8-GAA T-N11-A/TTA-N7/8-GAA T-N11-A/TTA-N7/8-GAA T-N11-A/TTA-N7/8-GAA T-N11-A/TTA-N7/8-GAAig. 2b).
The nanowire's response mechanism to hydrogen peroxide is also discussed in terms of the synergistic activity of the bimetallic binding sites, which has important implications for a better design of functional nanowires as sensing materials for a wide range of applications.
To predict the putative STAT3 binding sites on precursor region upstream of the miRNA sequence, we considered the list of miRNAs predicted to have putative STAT3 binding sites which has been recently reported [ 16, 17].
Under this scenario, one would expect MBG to be located close to DCC binding sites, which has been observed for head and brain (Chang et al. 2011; Catalán et al. 2012).
This means, that the adsorption of GTFs to a multitude of oral bacterial species may only work with the existence of universal binding sites, which has to come along with some degree of conservation of the gtf-gene for proper biofilm formation in the human oral cavity.
