Sentence examples for binding site which can from inspiring English sources

The rat theta-class glutathione transferase T2-2 (rGST T2-2) presents an ideal scaffold for the design of a novel GPX catalyst because it already binds GSH and contains a serine close to the substrate binding site, which can be chemically modified to bind selenium.

AES is an enzyme-inhibiting aptamer bearing a target-molecule binding site which can allosterically control enzymatic activity.

These analogs serve as useful molecular probes to explore the secondary binding site, which can be exploited in designing more potent DAAO inhibitors.

The −1195 A→G polymorphism creates a c-MYB binding site, which can activate COX-2 expression, and displays a higher promoter activity [15].

This surface coincides with a distinct binding site, which can accommodate either Ub or the Ub-like domain of HHR23 proteins (26).

The data therefore provide a model of the agonist binding site, which can be used for further structure−activity studies and rational drug design.

This is of special relevance as FN has many cryptic binding sites which can be unmasked and exposed by sGAG binding31,44,51.

Thus, the attachment of streptavidin to the biotin-terminated patterns leaves some biotin unoccupied binding sites, which can be used subsequently to pattern other biomolecules that are conjugated with biotin.

Computer simulations have shown that this is indeed the case for eukaryotic transcription factor binding sites, which can appear neutrally within microevolutionary timescales [13].

Second, the short-life of protein chromatin interactions continuously makes available binding sites which can then be scanned by diffusing transcription factors.

The structures show that CYPs have large, flexible binding sites, which can accommodate more than one substrate molecule, and allow for mutual influences of chemicals, which can act as substrates, activators, or inhibitors.