Sentence examples for binding site were retained from inspiring English sources

First, only alignments that had both putative exons and introns within 100 bases of the binding site were retained.

Here, we used ChIP-seq to generate genome-wide binding profiles of C/EBPα and PPARγ in human SGBS adipocytes, compared these to previously published profiles in mouse 3T3-L1 adipocytes [ 15, 16], and systematically studied what features affect whether a binding site is retained between species or not.

This denotes that the Oct-1, CREB and possibly Sp1 are necessary for full cell specificity, because the Oct-1 but not the CREB and Sp1 binding sites were retained in the deletion.

Consistent with the species specificity of transcription factor binding sites, Rosen and colleagues recently compared PPARγ binding in 3T3-L1 andpocytes and in vitro differentiated primary human adipose stromal cells (hASC), and found that only 21.3% of the murine binding sites were retained in human adipocytes.

Age and study site were retained in the multivariate model.

While previous reports agree that retention of transcription factor binding sites is limited, systematic analysis of the biological features determining whether a site is retained or not has not been performed.

Hypomorphic mutation in the NBS1 gene in question, results in transcript truncated for the N-terminal portion thus lacking FHA and BRCT domains, whereas the C-terminal domain containing MRE11-binding and putative ATM-interaction motif sites are retained [ 23].

Hits retaining interactions with the common amino acids of GSK-3β binding site were taken to represent potential leads.

The size of the binding site was also calculated using SiteMap, but this property was not retained.

We then measured the fraction of mouse C/EBPα and PPARγ binding sites that was retained and lost in human.

Otherwise, this binding site is regarded as an incorrectly predicted binding site.