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Amino acid variations at binding site were found to be more than other part of alleles.
In addition, both motifs required for NIM1-INTERACTING (NIMIN) protein binding, the LENRV motif and a NIMIN binding site, were found in PhaNPR1 (Figure 1B).
Mutations near the substrate binding site were found to reduce cellobiose inhibition, but in most cases (except G234S) the mutations also resulted in reduced thermal stability.
Only three instances of a possible binding site were found in these searches, all of which are located in the upstream regions of the most strongly regulated genes, by name cg1514, cg3138, and cysI.
Indeed, in support of this model, mutants in cof1 that disrupt its second F-actin binding site were found to be hyperactive for filament severing (Aggeli et al. 2014).
Since ten rare SNPs within the region between -4547 bp and -3489 bp, comprising a p53 binding site, were found at a higher frequency among the ten LLI relative to the Utah/CEPH population, we were interested to determine if the presence of these minor alleles affects the basal activity or p53 dependence of the p21 promoter.
Similar(53)
The lower binding site was found more constructive favorable for binding.
When peptide CTWW (CW-4) was introduced as the reference, the same binding site was found.
A specific ammonium ion binding site is found at the extracellular entry site of E. coli AmtB.
The glutathione binding site is found to be different from that of the canonical soluble glutathione transferases.
An SP1 binding site was found at postion −188 to −203.
More suggestions(19)
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