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Regions containing a deeply shared TF binding site were also more likely to have combinatorial TF binding and to be tolerant of genetic variations within bound motifs.

The roles of the charged and hydrophilic residues located in or close to the alleged binding site were also investigated by mutagenesis experiments: the results showed that two arginines, Arg and Arg, are crucial for the binding of GABA and/or for receptor function (6).

Promzea-predicted Motif1 or Motif5 were also retrieved in four out of the five input promoters shown experimentally to contain a P binding site in their promoters; copies of the P binding site were also predicted in the first 200 bp of the promoter of PAL1, encoding phenylalanine ammonia lyase.

The implicated regions of enzyme activity and glutamate binding site are also shown.

The sequence of osa-miR1436 along with its binding site is also shown.

The size of the binding site was also calculated using SiteMap, but this property was not retained.

In the same crystal structure, a similar ligand binding site was also observed in the symmetric position in CTM.

This Dim1 binding site is also consistent with recent crosslinking data ([25] and Figure S2).

And, this binding site was also crucial for inducing human β-defensin 2 by LPS in RAW264.7 cells [53].

The SEBF binding site was also identified in the MIR168 promoter.

The nucleotide sequences adjacent to the miR-1273g-3p binding site are also very homologous.