Sentence examples for binding site we found from inspiring English sources

When several known factor Xa inhibitors were overlaid within the protein binding site, we found that they all bind within the groove formed by the S1 and S4 sub-pocket of fXa (Figure 10B).

Site1, the binding site we found by DS2.1 automatically searching, can cover the structural domain included by endogenous ligand.

Interestingly, using a reporter system containing Nanog response element (binding site), we found that Li significantly enhanced the expression of reporter in HEK293T cells co-expressed with Nanog.

While the human tetherin cytoplasmic tail contains a predicted TRAF6 binding site, we found that this interaction was actually determined by the adjacent endocytic motif YDYCRV.

Other novel motifs were also found, but these were all accompanied by a conserved motif in the other binding site, we found RKVA and RRLW in BM1, and REYL and RRFL in BM2.

Scanning the whole protein without using any prior knowledge of the binding site, we find that the best scoring conformation in rhodopsin is 1.1 Å CRMS from the crystal structure for the ligand atoms.

Using chromatin immunoprecipitation (ChIP) and primers designed to flank these YB-1 putative binding sites, we found evidence that YB-1 binds to the SOX2 promoter at two adjacent regions.

Among GR binding sites, we found that 46%% occur at enhancers having all three marks.

Despite the co-localization of AGO1 with CTCF and HP1α binding sites, we found a weak but independent binding motif for AGO1.

Moreover, when we broadly searched PlasmoDBv10.0 transcripts for human microRNA binding sites, we found thousands of significant hits and that 61 transcripts harbored at least 100 predicted binding sites for a given human microRNA (p-value < 0.05) [Additional file 32].

Although the computational sequence analysis of 2.2 kb upstream of the pre-miR-29b1 stem indicated four putative CEBP binding sites, we found that none of them was CEBPA responsive in luciferase assays (data not shown).