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The TF binding site was predicted using an online database RegPrecise (http://regprecise.lbl.gov/RegPrecise/index.jsp) and Target Explorer (http://te.cryst.bbk.ac.uk/).ac.uk/
The CRLI carbohydrate binding site was predicted by docking with a specific inhibitory trisaccharide.
Furthermore, a DNA binding site was predicted in this protein model.
The substrate binding site was predicted by using the CastP server [34].
However a binding site was predicted by the RNA22 algorithm which does not rely on cross-species conservation of binding sites for prediction.
(57) An additional binding site was predicted near the 2′-OH nucleophile.
Similar(47)
The amino acid residues (Met1, Asp2, Glu43, Ala44, Glu47, Lys51, Ala157 and Leu158) lining in the binding site were predicted using SiteMap.
An edge f→g is added to the graph only when at least one binding site is predicted around the target gene, so when sf,g≥1.
The nonlocal nature of the protein-ligand binding problem is investigated via the Gaussian Network Model with which the residues lying along interaction pathways in a protein and the residues at the binding site are predicted.
Important amino acid involved in ligand binding site is predicted by this server.
On an average, atleast two residues per binding site were predicted to have ∆∆G score ≥ 0.5.
More suggestions(19)
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