Sentence examples for binding site was not from inspiring English sources
The last binding site was not observed in previous crystallographic studies.
As SSR504734 is a structurally analogous compound to [11 C]N-methyl-SSR504734, the possibility of interaction at a nonspecific binding site was not completely excluded.
After reconstitution of the donor and acceptor sites, the RC photocycle was also restored, i.e., the accessibility of the secondary quinone site and of the cytochrome binding site was not blocked in the PSiMc matrix.
On the other hand, the mutually exclusive C-terminus fragment 400-stop with an intact SH2 binding site was not sufficient to interact with tensin2 (Fig. 2B).
In the case of one of the miR-148 binding site, 148/152A, only 4 bases were mutated as a clone with the fully mutated binding site was not generated successfully.
As controls, HES1 3'UTR mutated in the miR-199b-5p miR-199b-5p miR-199b-5pfected binding199b-5p (Text siteFig. S1E), and wasnot 2-O'-methyl oligoribonucleotide (2-OM) complementaffectedature miR-199by5p miR-199b-5p miR-199b-5p miR-199b-5p TexteffectS1oFigiR-199b-5p transfection, restoring reporter activity (Text S1, Fig. S1E).
Dashes indicate that the actual binding site is not found within the five largest predicted pockets.
An interaction within the cofactor binding site is not necessary to obtain this high binding affinity for substances developed.
In both cases, the binding site is not inside the channel cavity and thus there are six equivalent binding sites due to the six-fold symmetry of the p7 channel.
In BD, previous knowledge and restriction of the search to a primary binding site are not necessary, and therefore, it can be used in search of multiple binding sites, as well.
