Sentence examples for binding site that involves from inspiring English sources

The designated binding site 1 in our crystal structure is DCC-specific, exclusively involving the FN5 domain of DCC and the EGF3 domain of netrin-1, whereas the designated site 2 is a unique and highly conserved anion-dependent binding site that involves both the FN5 and the FN6 domains of DCC engaging the EGF1-EGF2 dofains of netrinetrin-1

These include 1) a high affinity binding site that involves residues at the helix D AB loop interface, and 2) a low affinity receptor binding site that lies within the AC helical bundle.

The di-phosphorylated peptide is accommodated on a binding site that involves the top surface of the 8-bladed WD40 β-propeller domain of Fbw7 (Hao et al., 2007 ).

Also in this case, a di-phosphorylated peptide is accommodated on a binding site that involves the top surface of the 7-bladed β-propeller domain of β-TrCP (Wu et al., 2003 ).

Traditional peak calling methods are inadequate when identifying multiple TF binding sites that involve long genomic regions and therefore we designed a ChIP-seq processing pipeline for the detection of peaks via a combinatorial fusion method.

The NOS2 promoter also has a C/EBPβ binding site that is involved in gene induction in response to TLR and IFN-γ stimulation [58].

Cherrier et al. suggested that NikA binds Ni chelated by a small organic molecule, such as butane-1,2,4-tricarboxylate (BTC), and that some residues, including Tyr402, Arg137, Arg97 and His416, form a binding site that is involved in the BTC-Ni-NikA interaction [ 78].

The DNA region we refer to as island 4 is positioned next to an estrogen responsive element (ERE) binding site that could be involved in breast cancer.

Endothelin 2 (EDN2) is another example for a gene with a putative promoter HIF1 binding site that could be involved in the differential expression of genes in the CoCl2 treatment.

This again suggests that there are residues involved in directing the inhibitor to its final binding site that are distinct from those involved in the final high-affinity binding site.

This region is expected to contain most of the binding sites that are involved in transcription initiation [ 7, 8].