Sentence examples for binding site that appears from inspiring English sources

Further, 5 of these genes are known to also contain a CDE/CHR binding site that appears to be functionally dominant (Table 3B).

In addition, the C-terminal domain possesses a nucleotide-binding site that appears to exhibit allosteric control over the N-terminal ATP-binding site and may serve to elicit opening of the Hsp90 homodimer.

Importantly, GeF-seq could resolve the closely positioned binding sites that appear as one peak in the ChAP-seq method, as shown in Fig.  3A.

The largest set of developmental TF binding sites that appear on Alu belong to hemateopoietic transcription factors [ 43] such as Gfi-1, LYF-1, GATA3, GATA2 and ONECUT2 (Table 4).

A typical case study for motif discovery has been the analysis of sequences (e.g. promoters) from genes showing similar expression patterns and likely to be bound by the same set of transcription factors, in order to identify their putative binding sites that should appear to be overrepresented in the sequences.

The remaining 10,000 binding sites that did not appear in the MACS-predicted site list were further evaluated for the presence of the previously described CTCF motif.

We also used this method to identify genes that are repressed in diploid cells but that are not direct targets of the complex, as well as functional a1- α2 binding sites that do not appear to repress transcription in their genomic context.

Importantly, this evolutionary engineering of new CTCF-binding events appears to create binding sites that function as chromatin domain insulators and transcriptional regulators (Schmidt et al. 2012).

The existence of large numbers of transcription factor binding sites that have no apparent biological activity would appear to be a property of all eukaryotic organisms [61].

However, Puf proteins appear able to interact with RNA binding sites that vary substantially in sequence outside of their UGU core.

The rearrangement seen with the 357 372 dityrosine bridge appears to alter the zinc binding sites and open up buried binding sites that are not present in molecules lacking dityrosine bonds (Fig. 6B).