Sentence examples for binding site suggests that from inspiring English sources
An in silico search for inclusion of this polymorphism in a putative ESE for SRp40 binding site suggests that rs3790261 may affect the posttranscripional regulation of SLC24A3 mRNA, thus representing a RNA splicing signal.
The identification of a consensus sequence in over half of PARP3-bound sequences that matches part of the REST binding site suggests that PARP3 could interact with many of its target sequences through another transcriptional regulatory complex comprising REST.
The proximity to the Kac binding site suggests that this insert may play a role in recruitment of acetylated binding partners.
Nevertheless, SFN's effect on de-methylating the c-Myc binding site suggests that restoration of transcriptional expression of cyclin D2 may be dependent on c-Myc trans-activation.
Unmodeled electron density contoured at 2.5σ in the substrate binding site suggests that E2 and TBBPA are competing for the same binding site.
The additional sensitivity of transcriptional stimulation to alanine substitutions of disordered residues flanking the CycT1 binding site suggests that the flexibility and potential interactions with other ligands are important for function.
Nucleosomes of African green monkeys are also preferentially positioned but do not depend on the canonical CENP-B binding site, suggesting that histone-DNA sequence affinities or other proteins may influence the placement of nucleosomes [ 17- 22].
Thus, consideration of only the binding sites suggests that genes with similar binding properties are present in both species and that both humans and mice can detect Iva (possibly with similar capacity), in agreement with the finding of O'Connell et al. To date, the functional variability within and between OR gene repertoires has been assessed by considering overall protein similarity [7], [14].
The finding that 3/4 of the overrepresented motifs upstream of these late-peaking genes are potential ApiAP2 binding sites suggests that ApiAP2 proteins are important regulators in the later stages of the parasite's intracellular life cycle.
Our previous studies on rice miRNAs and miRNA binding sites suggested that positive selection and nucleotide mutations play an important role in co-evolution of miRNAs and their targets [ 18, 19].
