Sentence examples for binding site or the from inspiring English sources

This had no noticeable affect on the downstream ribosomal binding site or the expression level of YFP.

Silencing was also examined in strains containing mutations in either the ORC binding site or the ABF1 binding site of the HMR silencer (Figure 4A, [32]).

This observation suggests that E457Q alters the phlorizin binding site or the allosteric coupling of phlorizin binding with the inhibited state.

Bioinformatic analyses have predicted that the human pathogenic mutations, which are not restricted to a specific domain or region within the enzyme, could affect the substrate binding site or the dimerization interface of TPI [2], [13].

Third, we observed that mutating either the LC8 binding site or the NLS site abrogated the capacity of human Pak1 to rescue the defects caused by zebrafish Pak1 knockdown.

However, in contrast to the region around p300-2, we did not find increased recruitment of γ-H2AX, a known marker for DSB, in either the −4021/−3767 around the p300-1 binding site or the −825 to −567 region around the p300-3 binding site by UV irradiation.

Short oligonucleotides containing the two first AP-1 binding sites or the third AP-1 binding site, respectively, were previously demonstrated by our laboratory to bind in vitro affinity-purified AP-1/c-Jun or AP-1 present in PMA-treated HeLa nuclear extracts by EMSAs (competition experiments) [7].

These factors remain unknown but could include the distance between antigen binding sites or the flexibility of the carrier.

In clinical strain S. aureus (resistant to CIP) there were no significant changes in Fmax⁡, number of binding sites, or the K d value.

This binding can be affected by single-nucleotide polymorphisms or indels in the miRNA target site leading to the suppression of existing binding sites or the generation of illegitimate ones.

Perhaps the other binding sites or the steric availability of the NF- κB binding site, whose cognate transcription factors have also been shown to interact with both HDACs and HATs, led to interactions of the Sp factors or NF- κB heterodimer with HATs due to the presence of the HDAC inhibitor and TNF- α.