Sentence examples for binding site of small from inspiring English sources
Recent work from our group also highlights the importance of photo-cross-linking in elucidating the binding site of small molecule and peptide ligands on GPCRs.
The insets show magnified images of chain structures in bright field and fluorescence mode (structures equivalent of C3 in Fig. 1c), indicating the location of the binding sites of small particles in the aggregates.
An NMR method was developed for determining binding sites of small molecules on human serum albumin (HSA) by competitive displacement of 13C-labeled oleic acid.
The small organic molecule or peptide used as ligand, binds to its binding site, and the attached polypeptide finds and occupies the most favourable site of interaction on the protein surface in close proximity to the binding site of the small molecule [ 15].
Since ATP binding is the initiating catalytic step, targeting the ATP binding site of PKN1 3 with small molecule inhibitors would likely be an effective route to block enzymatic function.
Since the binding site of LYN is smaller than the binding site of Plk1, molecule A was designed to be too big to fit into the LYN binding site, but small enough to fit into the Plk1 binding site.
For example, the well-characterized GTP binding site of the Ras family of small GTPases is divided into four small sequence regions.
Another plausible explanation for our results is that the new predictions are enriched for binding sites of a small number of TFs that, for an unknown reason, show exceptionally good correlations between PWM score and expression change.
SiteMap analysis suggests that the binding site of model 1 is smaller than that of model 2 (Table 1).
Given the promiscuity of the rest of the binding site to small-molecule structures, the method of classification of CYP51 inhibitors by Fe-coordinating heterocycles has demonstrable utility.
Computational design of protein ligand interfaces finds optimal amino acid sequences within a small-molecule binding site of a protein for tight binding of a specific small molecule.
