Sentence examples for binding site of several from inspiring English sources
According to FuncPred, this SNP is changing the binding site of several transcription factors, however, without any predicted functional consequences.
In addition, the BIR domain has a regulatory function as the binding site of several IAP antagonists such as SMAC/Diablo and HtrA2.
Tyrosine kinase inhibitors (TKI), being analogues of ATP, compete with the ATP binding site of several oncogenic tyrosine kinases, hence blocking their signaling pathways involved in the phosphorylation of cellular signaling proteins which is essential for tumor cell survival and proliferation.
Specific GAG binding sites of several chemokines have been delineated by mutagenesis, demonstrating that these sites are either distinct, or partially overlap with receptor binding sites.
Previous efforts were made to tackle this task by considering the fact that TF binding sites tend to be more conserved than other functional sites and the binding sites of several TFs are often clustered.
Surprisingly, binding sites of several members of the forkhead family of transcription factors, that are however not well characterised were also significantly found to be overrepresented in our dataset.
In line with this, we found that binding sites of several transcription factors related to proliferation/differentiation, including E2F, c-myc and p53, are enriched in the promoter regions of RNA processing genes (Figure S11), which included more than half of the poly(A) genes, and factors in E2F and pRB families were reported to bind promoter regions of genes encoding CstF factors [52].
In these regions a number of binding sites of several trancription factors are located, which are important for viral gene expression.
The binding sites of several miRNAs are located in the 3′UTRs of some orthologous genes in the Drosophila genome and have highly homologous nucleotide sequences [ 30].
Moreover, the binding sites of several TFs were found to co-occur with NF-κB and IRF sites in sets of genes with similar expression patterns in dendritic cells after Toll-like receptor stimulation.
