Sentence examples for binding site of a from inspiring English sources

In summary, we describe the intrahelical binding site of a highly potent, specific CXCR3 antagonist.

Ligand binding site of a fraction of integrin αIIbβ3 becomes activated on agonist induced platelet aggregates at stenosis.

To identify locations on the Rv3 oligosaccharide at which to incorporate D3-like branches, the Rv3 crystal structure19 was modeled into the binding site of a PGT128 crystal structure21 using the UCSF Chimera software package46.

The ability of a peptide to react specifically with the functional binding site of a complementary antibody is known as its antigenic reactivity or antigenicity.

Computational design of protein ligand interfaces finds optimal amino acid sequences within a small-molecule binding site of a protein for tight binding of a specific small molecule.

This review discusses the major methods and programs specifically developed for the purpose of designing combinatorial libraries under the constraint of the binding site of a biological target, with emphasis on their advantages and disadvantages.

With the growing understanding of the molecular biology of protein tyrosine kinases and the use of structural information, the design of potential drugs directed towards the bind adenosine triphosphate (ATP -binding site of ATP -bindingget hasitecofe possible.

The metal-binding site of a Helicobacter pylori ATPase 439 (heliWT-tag) was successfully used as a new fusion peptide for immobilized metal ion affinity chromatography (IMAC).

The crystal lattice revealed an interaction between eight sequential residues in one iASPP molecule and the p53-binding site of a neighboring molecule.

Based on the crystal structure of human glutathione transferase M1-1, cysteine residues were introduced in the substrate-binding site of a Cys-free mutant of the enzyme, which were subsequently alkylated with 1-iodoalkanes.

This system, Light-Inducible Transcription using Engineered Zinc finger proteins (LITEZ), is based on the blue light-induced interaction of GIGANTEA and the LOV domain of FKF1 that drives the localization of a transcriptional activator to the DNA-binding site of a highly customizable engineered zinc finger protein.