Sentence examples for binding site is small from inspiring English sources

Exact(3)

The sialic acid binding site is small, deep, and highly polar.

The size of this binding site is small in comparison to the P-master fragments and cannot explain the conservation over ~100 bp.

The MG-H1 binding site is small, spanning 80 Å, and fits well into a groove formed by strands C, F, and G; side chain interactions provide additional stability for MG-H1 binding.

Similar(57)

Based on sequence and structural data of riboswitches, it has been calculated that for some amino acids (arginine, histidine, isoleucine, leucine, phenylalanine, tryptophan and tyrosine) the chances that the coding triplets are evenly distributed in the binding site are small.

The central β-sheet region, which formed part of the RNA-binding site, was smaller in NVAV than in most other N proteins.

This requirement restricted us to using relatively subtle mutations and therefore the impact of the mutated binding site is relatively small.

The observed halide binding site is quite small, with several enzyme−Cl− distances of <3.5 Å, which would favor Cl− binding over Br− or I−, but it will be mechanistically interesting to determine whether I− can access this site.

C-terminal from the AP-2 binding site is a small motif present, which is responsible for a direct binding to γ-adaptin, a component of the AP-1 complex ([ 44, 45].

Because the number of observed evolutionary differences in any particular binding site is typically small, I make the assumption that each DNA difference in a transcription factor binding site occurs independently, and presence of a single change has no effect on the probability of other changes.

A potential protein ligand binding site is one predicted by fpocket to bind small molecules, whereas a known protein ligand binding site is one that has been experimentally shown to bind small molecules.

Although identifying a minimum set of stereochemical properties consistent with a small-molecule binding site is challenging (Hajduk et al., 2005; Pérot et al., 2010), the increasing number of ligand-protein and protein protein structures in the Protein Data Bank (PDB) provides a foundation to explore this important problem with respect to PPIs.

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