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Exact(14)
It remains elusive whether the H epitope/acetamido binding site is required for the Le binding strains that do not bind the H antigen.
The promoters of nearly all the target genes we identified have putative TCF binding sites, and we show that the TCF binding site is required for induction of Follistatin.
Analysis of the CD155 core promoter indicates that an intact GLI binding site is required for Shh activation.
Taken together, these results further suggest that SRF and TFAP2 are transcription factors important for frataxin expression, and the intronic sequence downstream of exon 1 which contains a putative EGR3 binding site is required for full expression of frataxin.
Although the enhancer element of Otud-6b from −1515 bp to −1397 bp of Otud-6b is structurally different from those of Dub-1, Dub-1a, and Dub-2a, the functional transcription factor binding sites are very similar as the conserved ETS binding site is required for Otud-6b enhancer activity as well (Figure S9).
Because the same binding site is required for interaction of plakoglobin to α-catenin, the latter is excluded from desmosomes.
Similar(46)
A functional Rab9 binding site was required for TIP47 stimulation of MPR transport in vivo.
Based on the mutagenesis results of the WNV MTase, it was proposed that two distinct sets of amino acids on the enzyme surface (including residues in the RNA binding site) are required to reposition the RNA cap during the N7 and 2'-O methylation events [24], [28].
As shown in Figure 4A, the sequences between -586 and -830 were required for activity of the 14-3-3γ 14-3-3γ 14-3-3γat the compromoter3 consensus binding site wandrequired for suppression of reporthatactheity in response to ionizing radiation.
Interestingly, all five of the protonatable residues within the binding site are required for transport as none could be mutated and still allow for the transport of either peptide.
For restoring of the binding, a minimum of two anti-slan binding sites is required although three binding sites are clearly superior.
More suggestions(16)
binding capacity is required
binding site is based
binding protein is required
binding element is required
binding site is related
binding specificity is required
binding mechanism is required
binding site is located
binding site is shifted
binding activity is required
binding pocket is required
binding effector is required
binding information is required
binding site is outlined
binding site is increased
binding site is buried
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