Sentence examples for binding site is likely from inspiring English sources
Notably, as shown above, "c-Jun bind 1" bound the mtDNA stronger as compared with "c-Jun bind 2" (fig. 3), thus suggesting that the stronger binding site is likely more functionally important than is the weaker site.
The predicted ligand binding site is likely to be in the very end of the C-terminal portion.
Considering that the orientation of the lipid within the CD1d binding site is likely to affect the positioning of the head group, these data suggest the surprising possibility that a single type of phospholipid might present two different epitopes for TCR recognition depending on the orientation of binding within the CD1d groove.
Effects of SNPs in the binding site is likely not simple.
The effects of SNPs in the binding site is likely not simple.
Author's Response The role of the putative second NADPH binding site is likely to activate the enzyme.
Deviation in amino acid composition between AChBP and nicotinic receptors, particularly in the complementary face of the binding site, are likely causes for the observed SAR differences.
In addition, the steric and electrostatic properties of the binding site are likely to play a key role in the placement of the thioester moiety in register with the catalytic residues, as required for productive substrate binding, a determinant of turnover rate (kcat).
However, recent data have implicated that σ2 binding sites is likely to be the progesterone receptor membrane component 1 (PMRMC1) or within PMRMC1 complex which shares homology with cytochrome b 5, a heme-binding protein that activates cytochrome P450 proteins [18].
In light of the significance of this loop domain for binding MLL, this long-range dynamic coupling between the two binding sites is likely of functional significance.
The specificity of these similar binding sites is likely to be achieved through the competition among homologous TFs for the same binding site, which is governed by their thermodynamic equilibrium [ 48].
