Sentence examples for binding site is consistent from inspiring English sources
This location for D2 adjacent the pABA binding site is consistent with the presence of sulfonamide resistance mutations within this loop region.
DOI: http://dx.doi.org/10.7554/eLife.03080.016 The identified binding site is consistent with mutations of Arg149 and Arg150 of uS11 in Chinese hamster ovary (CHO) cells that have been found to confer resistance to emetine (Madjar et al., 1982).
The involvement of the carboxylate of 6 in strong polar interactions within the binding site is consistent with known SAR in this series: The inactivity of ester prodrug 7 and its congeners is indicative of the need for a free carboxylate.
Structure-activity data on chemical derivatives, sequence analysis of Eg5 homologs from different species, and the effect of mutations near the drug binding site were consistent with the crystal structure.
These weaker interactions with the second binding site are consistent with the negative cooperativity between these sites that is observed with T4 (Ferguson et al. 1975).
The presence of both ferrihydrite and goethite binding sites is consistent with the X-ray diffraction results, which indicate that the nanoparticle suspensions exhibit features consistent with both ferrihydrite and goethite (Figure 1).
This indicates that our genome wide analysis of in vivo binding sites is consistent with previous studies on the half-site for binding of LRH-1 (5'-CAGGGTCA-3') '[ 17].
Pparγ is both necessary and sufficient for adipocyte differentiation of fibroblast/pre-adipocyte cell lines[ 24] and the presence, in all the Nnat promoters analysed here, of Pparγ binding sites is consistent with it playing a role in regulation of Nnat expression in WAT.
The overlap of Atg18p and Vac7p sites at a position close to the Fab1p-binding site is consistent with competitive regulation of Fab1p by its positive and negative regulators.
