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A binding site is considered to be conserved if its score meets the threshold score for its binding matrix in all 3 species.
Although the TLR4 promoter region has no direct STAT3 binding site, its PU.1 binding site is considered to be one of its main regulatory elements and STAT3 has been shown to be capable of activating PU.1 [51].
For QSAR model development, the receptor binding site is considered to be rigid and the ligand molecules should belong to a congeneric series [ 37].
A binding site is considered to be conserved across the alignment results if its score is no less than the threshold score.
The assessment requires appropriate assignment of a binding site to the target gene: generally a binding site is considered to influence the expression of a gene if it lies within a predefined window around the TSS or the gene.
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The molecules with a maximum of at least 2 H-bonds with the hinge region at the ATP binding site were considered along with any one of the rings.
Three properties of the binding site were considered: the total number of atoms at 4 Å from its surface, its hydrophobicity, i.e., the fraction of carbon atoms among this total number, and its exposure to the solvent.
Only genes containing both a potential core binding site and a potential half binding site were considered as positive for the presence of a "complete QRE".
The side chains of residues surrounding the binding site were considered flexible.
Promoters overlapping with an ETS binding site were considered as ETS factor bound promoters.
A CTCF binding site was considered a constitutive binding site when the same motif site was present in more than 90% of the 55 cell lines.
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binding site is viewed
binding site is accommodated
binding site is in
binding site is at
binding site is created
binding factor is considered
binding site is checked
binding strength is considered
binding pocket is considered
binding site is located
binding site is shifted
binding site is comprised
binding site is outlined
binding site is composed
binding site is conserved
binding reaction is considered
binding domain is considered
binding site is blanked
binding site is provided
binding hamiltonian is considered
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