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The N-terminal binding site is additionally dependent on membrane curvature, the fragment binding less efficiently to more highly curved membranes (Supplementary Figure S4).

Additionally, the dephosphorylation of the binding site is only possible if the site is not occupied.

Otherwise, this binding site is regarded as an incorrectly predicted binding site.

Additionally a Pum1 binding site was predicted in the 3′ UTR of Sox2.

Additionally, the number of SNPs found in the predicted transcription factor binding sites is higher than in non-binding site sequences.

Additionally, Sp1 binding sites are found in the promoters of many housekeeping genes (Black and Azizkhan-Clifford, 1999).

Additionally, some binding sites are present in the nucleotide sequences but are not involved in the regulation of genes in certain conditions by being inactive [ 23].

Additionally, AR binding sites were enriched with sequence motifs recognized by the ABDB (Abdominal-B type homeodomain transcription factors) family (Additional file 3: Table S3), suggesting potential combinatorial control between androgen receptor and homeobox genes.

Additionally, when the binding sites were preoccupied with free testosterone, the number of binding events dropped down to 67 from 183 detected interactions in the case of sbAvd-1.

Additionally, the properties of binding sites were studied for mRNA sequences of both human and other animal species.

Additionally, new p53-occupied binding sites were identified for the MDM4 and dyrk3 genes, for which different p53 binding locations have previously been described [ 5].