Sentence examples for binding site in close from inspiring English sources

We found that the miR-181a/-2a* miR-181a/-2a* miR-181a/-2a*inding site in close precursor to its TSS (Table  3), suggesting its direcontainsation of theSOX2iRNAs.

However, we were able to enhance the discrimination of KOD exo- by increasing the steric crowding of the template binding site in close vicinity to the residues bearing the C or 5mC of interest.

In this regard, HDAC family member 8 appears to be an attractive target, as crystal structure analysis revealed a unique second metal binding site in close proximity to the main catalytic domain, which distinguishes this HDAC isozyme from the other classical deacetylases.

We conclude that it is unlikely that there exist two tropane binding sites in close proximity to one another on either the DAT or SERT.

In support of this possibility, there are HIF binding sites in close proximity with the XBP-1 "A" site occupied in response to ER stress (Figure 4B) in all three species.

Chromatin remodeling might then involve making only subtle alterations to a distinctive chromatin higher-order structure already possessing transcription factor binding sites in close proximity in three dimensional space.

The presence of multiple binding sites in close proximity significantly increases the probability of interactions between miRNAs and mRNAs, even if mutations occur.

Although C/EBP is also described to have binding sites in close proximity to NF-κB TFBS, promoter analysis did not reveal its significant overrepresentation.

Long and unusually highly conserved motifs may provide a highly specific site or several binding sites in close proximity to ensure a coherent regulation of the respective genes, at least in one biological process or response.

Statistical analysis (Zhang et al., 2008) derived a total of 774 Red1 binding sites, in close agreement with previous reports, which identified 656 and 802 axis association sites, respectively (Panizza et al., 2011; Blitzblau et al., 2012).

Bioinformatic analysis of ChIP-seq data demonstrated promoter occupancy of PPARβ/δ for some of these genes, and also identified the presence of other transcription factor binding sites in close proximity to PPARβ/δ bound to chromatin.