Sentence examples for binding site in both from inspiring English sources
Saturation binding experiments in membranes of transiently transfected cells expressing either the wild-type or the variant receptor revealed a single binding site in both cases and no difference in Bmax between both receptor isoforms.
This is in agreement with a previous report [55], which showed similar chemical interactions between quercetin and the residues of the binding site in both proteins.
These results showed that Luciferase activity increases in the presence of TCF binding site in both K562 and Lucena cell lines.
The binding properties of both receptors were similar, suggesting that ATP occupies the binding site in both receptors in a similar conformation.
Thus, even when two orthologous cis-regulatory sequences have been identified, it is difficult to know whether the presence of a binding site in both sequences is due to binding site turnover or chance.
In addition, we investigated the presence of β-catenin in the protein complexes formed at the TCF consensus binding site in both S4 and S5 oligonucleotides as these TCF binding sites showed the clearer and stronger signal in EMSA analysis.
It is noteworthy that FBL17 promoter sequence carries the canonical E2F binding sites in both A. thaliana and rice [28].
Despite the observed differences in telomerase expression between mammalian and zebrafish, we detected common transcriptional factor binding sites in both promoters.
As shown in Figure 6A and 6B, we observed robust complex formation with labeled probes corresponding to the GATA binding sites in both the UP1B and UP2 promoter sequences of RA-treated samples, while control nuclear extracts showed negligible binding.
The experimental observations were also supported by computational analysis of aggregation propensity profiles, demonstrating that the aggregation-prone regions are located in close proximity to the calcium- binding sites in both proteins.
Since Cry2Ab and Cry2Ae, but not Cry1Ac, share binding sites in both Helicoverpa species, the alteration of the receptor for Cry2A proteins is expected to confer resistance simultaneously to these two proteins without affecting the insect susceptibility to Cry1A proteins.
