Sentence examples for binding site implies a from inspiring English sources

This is counterintuitive since a strong binding site implies a long residence time in the channel.

As noncompetitive inhibitors, their binding to a site distant from the substrate binding site implies a conformational change that may be regulatory and not linear with substrate binding.

Only the (R -epimer of MG-H1 can be fit into the MG-H1–V domain binding site, implying steR -epimeric recofnition of MG-H1.

Well-positioned tag distributions were most prominent for the high-scoring sites, which often correspond to frequently occupied binding sites, implying that this pattern directly results from binding site occupancy.

Thus, calcitonin, calcitonin gene-related peptide (CGRP), adrenomedullin (AM) and amylin (AMY) are able to displace each other from specific binding sites, implying significant cross-reactivity of each of them with the receptors of other peptides.

However, studies on the SGCs suggest no evidence for a second covalent heme-binding site, implying that this histidine could have some other function.

1) "[S]liding off of target sites" implies a specific physical model in which Ago2 departs from its seed-matched binding site but not the RNA itself.

A significant portion of these candidate target genes contains evolutionarily conserved Ap2-binding sites implying that several of them are direct targets of the Ap2δ and Ash2l-containing HMT complexes.

The annealing caused numerous breaches, increasing the edges sites that have higher Li binding energies than the inner sites, implying a remarkable edge effect [9, 32, 33].

Two groups have provided interesting evidence that KSHV-encoded miR-K-11 and miR-155 share a common set of mRNA targets (BACH-1, FOS, and LDOC-1) and binding sites; this finding implies a possible link between viral- and nonviral-mediated tumorigenesis [ 71, 76– 76].

The absence of strong binding to the third site implies distortion of this remaining site, and hence of the UspA1 molecule.