Sentence examples for binding site has not from inspiring English sources

Finally, KJ-Pyr-9 was found to strongly bind to MYC, to the MYC-MAX heterodimer, and weakly to the MAX homodimer, but its binding site has not been precisely mapped.

Despite the well documented involvement of PPARγ in regulating hres expression in human macrophages, paradoxically PPARγ binding site has not been found within the hres regulatory sequences.

The binding site has not been mapped.

Thus far, a definitive halide binding site has not been established for vanadium haloperoxidases.

This hydrophobic binding site has not been observed in any extra-cytoplasmic thiol-disulfide oxidoreductases (TDORs) reported so far.

This could theoretically lead to increased levels of the enzyme, but use of the extra binding site has not been confirmed experimentally [ 5].

This chimera/mutation study illustrated the importance of transmembrane segments in capsaicin activation, however, many critical questions such as the location of capsaicin binding site had not been completely answered.

Although examples of association between BRG1 and TFs have been previously described (Trotter and Archer, 2008; Reisman et al., 2009; Euskirchen et al., 2011), this specific configuration of BRG1 binding to nucleosomes flanking the TF binding sites has not been generally recognised.

However, the above phylogenetic scoring methods require multiple alignments of orthologous genes from species being compared, and they suffer when the alignments contain inaccuracies or when the location or orientation of the TF binding sites has not been conserved (Moses et al., 2006).

Although the crystal structure of one of these domains has been determined by x-ray analysis, its connection to the other major domain that contains the guanosine-binding site has not been known.

However, the sequence of the Zfp637-binding site has not yet been elucidated and further experiments are needed to explore the Zfp637-responsive elements.