Sentence examples for binding site found by from inspiring English sources
In addition, some features of the negative modulator binding site found by means of the molecular dynamics study and pocket analysis can be used in the rational design of the allosteric NMDA receptor modulators.
The number of genomic COUP-TF HMM matches is high when compared to the number of nuclear receptor binding sites found by ChIP-based location analyses [2].
Indeed, most ChIP-based assays have only a partial overlap with binding sites found by computational searches, and most sites predicted in silico are not occupied by the cognate transcription factor when pursued experimentally.
This method of analysis will help with the problem of false positive binding sites found by computational methods.
We suggest, however, that binding sites found by ReXSpecies, which are included in an evolutionarily conserved module and which are gained or lost together, have a good chance of being "true positive".
Analysis of chromosome wide binding of the alternative sigma factor σ in Escherichia coli with this new protocol resulted in detection of only a subset of binding sites found in a previous study by Wade and colleagues.
Related studies on mycoremediation have indicated that contaminant heavy metals can be biosorbed by mushroom bodies at binding sites found in the cellular structure [20].
Moreover, this expansive active site merges seamlessly into a second peptidoglycan-binding site found in the second domain, extending the active site by an additional ∼30 Å.
Methods for computational enhancer discovery have commonly first attempted to identify the constituent transcription factor binding sites (TFBSs) based on the logic "find the binding sites, find the enhancer" [see reviews by [ 3- 5]].
Site1, the binding site we found by DS2.1 automatically searching, can cover the structural domain included by endogenous ligand.
When we used the Sry ORF (GenBank NM_011564) for the miR-138 binding site (CACCAGCA), we found 14 potential sites which is consistent with the number of sites found by Hansen and colleagues.
