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A putative binding site for classical, imidazole-derived H3 antagonists was identified by molecular docking.
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We used FIMO to scan ESR1 binding sites for classical ESR1 binding motifs drawn from the JASPAR database.
It appears that, at least for the human β1-adrenoceptor, some of the same residues are required by both conformations of the receptor and therefore the binding site for the classical catecholamine site and the secondary site must overlap to some degree [13].
cis-Decoder analysis also revealed that many of the conserved sequences contain DNA-binding sites for classical regulators of neurogenesis, including bHLH, Hox, Pbx, and Su(H) factors.
Sequencing of the Tgfa promoter revealed several potential E-box motifs, among which one in particular (nt −2360 −2330) was a perfect match to the classical consensus binding site for MITF (CACGTG).
The binding site for 1-trimethoxybenzyl group of 1, which distinguishes it from classical catecholamines, is unknown.
The binding site for pore blockers is indicated.
Our study revealed a nucleosomal DNA binding site for hORC1BAH.
The heparin binding domain 3 (HBD-3), also located at the C-terminal end, is the major binding site for most studied bacterial Vn-binding proteins8.
While the aldehyde-binding sites of ALDHs are as diverse as their substrates, the binding site for NAD+ of ALDHs has been known to be relatively conserved46.
A Drosophila Myb binding site, as well as the binding site for another Myb complex member (p120), is necessary in cis for replication of reporter transgenes.
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