Sentence examples for binding site could result from inspiring English sources

For example, a transcriptional suppressor protein that competes with a transcriptional activator for the same binding site could result in decreased activation through increased methylation [13].

While it is obvious that deletion of an SP1 transcription factor binding site could result in down regulation of Cox-2 as in the case of allelic variant 1 there is also justification that the insertion of multiple SP1 sites could also result in down regulation (allelic variants 2 and 3).

Any perturbation of a binding site could result in a functional effect, since reducing transcription factor binding will cause deregulation of the target gene, whereas introducing a new site could cause undesired transcription (De Gobbi et al. 2006).

Such heterogeneity in the primer binding sites could result in inefficient amplification of TC1507 DNA giving rise to the results seen with methods 2 and 5.

Either visfatin or molecules that fit visfatin's binding site could help control the disease.

This fortuitous binding site could later prove to be a useful binding site for other low molecular mass partners.

"Not only have we shown that serum amyloid A is a key protein trigger in sarcoidosis, but we also have evidence that the resulting inflammation is dependent on binding the protein at toll-like receptor-2, which opens up a host of possibilities that drugs blocking this binding site could prove an effective treatment for this disease," said Chen, an assistant professor at Johns Hopkins.

In a receptor where there are multiple potential ligand-binding sites, this could result in preferential binding only to sites where such repulsion is absent.

Such interactions between elements around the binding sites could easily modulate affinity resulting in autoinhibition.

Our results indicate that membrane testosterone binding sites could fulfill this definition, as they can aid in discrimination between benign and malignant/premalignant prostate conditions.

Both GR and BMAL1-CLOCK results demonstrated that the methylation of TF binding sites could influence the tested protein expression level (luciferase activity).