Sentence examples for binding site composed of from inspiring English sources
The result is a binding site composed of molecular fragments that can be treated as a target for molecular docking.
For instance, a combination of site-directed mutagenesis and gel permeation chromatography analysis revealed that ArsA had a high-affinity metalloid binding site composed of Cys113 and Cys422.
It also uncovered a putative FurA binding site composed of three repeated A/T rich regions between positions - 127 and +11 relative to the +1 transcription (Fig. 1a).
The interaction of bacterial ecotins with the active site of serine peptidases occurs via the primary binding site composed of the 50s and 80s loops, the latter bears the reactive Met84 residue (Yang et al., 1998).
This is rationalized by competition between phosphorylated T287 and T288 for a binding site composed of arginines, based on a structure of Aurora-A in which phospho-T287 occupies this site.
Based on the structure and binding measurements, the authors argue that the high affinity binding site composed of LysM1-3 is essential for the ability of ECP6 to suppress chitin-induced innate immunity.
These complexes bind to characteristic binding-sites composed of partially overlapping Pbx-Hox half-sites, frequently in conjunction with a distal Meis/Prep site [ 17, 18, 35, 36].
Rankin and colleagues propose a Parkin RING2 model with two Zn2+-binding sites, composed of residues C418, C421, C441, C436 and C446, C449, H461, C457 [ 34].
The primary binding site is composed of pyrimidine-specific binding clefts that are located in the N-terminal domains and anchor Rho to transcripts at C-rich Rut (Rho utilization) sites.
The composite picture derived from ligand binding and structural studies suggests that the binding site is composed of at least four subsites, each of which interacts with a single monosaccharide unit (Leffler and Barondes 1986; Knibbs et al. 1993; Hirabayashi et al. 2002).
Then the binding site is composed of residues within 10 Å from the ligand (Fig. 4b).
