Sentence examples for binding site close to from inspiring English sources
However, turnover/binding of short chain substrates is dramatically increased by introducing a novel substrate carboxylate binding site close to the heme.
We mapped the cation binding site close to the anion binding site and established a specific mechanism of inhibition occurring only in the closed conformation of the enzyme when the catalytic cysteine is phosphorylated and the catalytic aspartate moves into the active site.
DGAT1 contains a large hydrophobic domain, localizes in the endoplasmic reticulum (ER), can form homo-tetramers through N-terminal interactions (Yen et al. 2008), and has a potential DAG binding site close to the C terminus.
Under repressing conditions Pho2 occupied its binding site close to UASp1, but no binding was detectable at N-2 sequences (Fig. 5).
Interestingly, the murine MHC class I molecule H-Kb, which is structurally related to MHCII molecules, was suggested to adopt a supine (lying down) orientation on the membrane, with the peptide binding site close to the membrane (while remaining accessible to the T cell receptor and the CD8 coreceptor [40]).
The data suggest that the non-peptide antagonists occupy a binding site close to the interface of the N-terminal domains of CLR and RAMP1.
Therefore, it seems that differentiation related genes tend to have an OCT4 binding site closer to their TSS.
Nevertheless, the binding site closest to the core promoter is preferred (Lloyd et al. 1998; Estrem et al. 1999; Newlands et al. 1991).
These studies suggested a second binding site for palonosetron at the A+A− interface that was not found for granisetron; this was located below the 5-HT binding site, closer to the membrane.
We also removed all probes that contained human SNPs (MAF ≥0.05) or chimpanzee SNPs (MAF ≥0.15) within the last 5 bp of their binding site closest to the CpG being assayed.
By consequence, potential iron binding sites close to carbonylatable sites promote the effective oxidation of these sites.
