Sentence examples for binding site can result from inspiring English sources
The presence of an SNP on a binding site can result in several different effects.
Inactivation of a ligand binding site can result from absence of an antibody chain, inappropriate assembly, misfolding, or unexpected modification of the binding site, and will affect the response ratios.
The sensitivity of primers to sequence variation in primer binding sites can result in incorrect genotype assignment as described in Gaedigk et al. (2010).
Thus, it appears that since a single miRNA can regulate hundreds of targets, such a mutation in the seed region target-binding site can lead to a cascade effect, resulting in many secondary effects that eventually lead to deafness.
Ligand binding to the P-site can result in steric blockade of the A-site and inhibit substrate hydrolysis.
A variant, rs4820599, on the GGT1 gene is predicted to be located at a transcription factor binding site, which can result in differential gene transcription, according to FuncPred (http://snpinfo.niehs.nih.gov/snpinfo/snpfunc.htm, accessed 3/31/2015).
Similar to vinca alkaloids, maytansine and its analogs emtansine (DM1) which are microtubule-targeted drugs binding to tubulin at the vinca binding site can depolymerize microtubules and arrest cells in mitosis, resulting in a powerful anti-mitotic activity [7 10].
In both cases, the hidden binding site can be open spontaneously or as a result of allosteric interaction.
Our results suggest that the residues responsible for cation-binding in PpENA1 are distinct from those in fungal type IID ATPases, and that a fungal-type cation binding site can be successfully engineered into the moss protein.
Each hormone binding site can be divided into an inner and outer binding cavity.
