Sentence examples for binding site can provide from inspiring English sources
Thus, molecular imaging based on small molecule probes with intracellular binding site can provide more roundly information about the c-MET activation status.
Targeting the Abl myristate binding site can provide an important pharmacological tool to suppress the rise of drug resistant mutations, and overcome existent mutations that are resistant to ATP-competitive inhibitors.
These results provide strong biophysical evidence that allosteric interactions play a role in Abl kinase downregulation and that targeting sites outside the ATP binding site can provide an important pharmacological tool to overcome mutations that cause resistance to ATP-competitive inhibitors.
Therefore, each true binding site can provide up to 5 initial solutions that are similar to the real motif.
A structural mapping of protein binding sites can provide a useful tool for probing the three-dimensional structural relationships between biological macromolecules [3, 10].
Since many proteins conduct their molecular functions through the specific recognition of small molecules (ligands), information about the ligand-binding sites can provide insights into their molecular functions (Campbell et al., 2003; Sotriffer and Klebe, 2002).
The identification of different ligand binding modes to a secondary site can provide hints for the design of non-ATP-competitive inhibitors targeting the interaction between the α catalytic and the β regulatory subunits.
Since not all cis-elements are known and transcription regulation most likely results from the presence and a combinational use of multiple transcription factor binding sites [21], computational identification of such sites can provide a rapid and cost-effective method for identifying groups of co-expressing genes with high success.
The value of n of BSA at all three studied temperatures is approximately equivalent to 1 as fractional binding sites don't occur and no < 1 binding site can be present suggesting only one binding site for rivaroxaban.
Each hormone binding site can be divided into an inner and outer binding cavity.
