Sentence examples for binding site based on from inspiring English sources

Herein, is an account of synthesis and characterization of reasonably designed turn-on fluorescent probe SGPB1 with Salicylhydrazide as binding site based on BODIPY adapted fluorophore.

The Flpp3 structure demonstrates a globular protein with an electrostatically polarized surface containing an internal cavity a putative binding site based on the structurally homologous Bet v1 protein family of allergens.

Presumably the optimal binding site, based on the flexible information theory approach, is the most stable site and the easiest to crystalize.

Finally, the altered lipid binding site based on the basic collar and hydrophobic hairpin of vinculin tail may still be subject to regulation by protein phosphorylation.

Here, we rely on a prediction of the putative binding site based on the premise that orthologous OR genes are likely to have similar binding sites while the binding sites of paralogous OR genes are likely to be different [25].

The data indicate that G27, G125 and G9 have unique epitopes: while G9 and G125 may recognize same binding site based on their blocking patterns, G27 and G125 do not necessarily share the same epitope.

In related studies, Tsuchiya et al. [ 3] used a structure-based method to identify protein-DNA binding sites based on electrostatic potentials and surface shape.

The co-crystallized ligands are subsequently transposed between similar superimposed binding sites based on the translation and rotation matrices obtained with binding site superimpositions.

With KDE, the method could probably be extended to cluster binding sites based on the partial charges of their surface atoms.

Kennewell et al. [10] developed a method for comparison and superimposition of all holo proteins in the PDB based on protein backbone atoms, which allows ligands to be transposed between protein binding sites based on protein structure superimpositions.

Two of them, the lid and β9 loop, expose a large hydrophobic surface and are considered as acyl chain binding sites based on their interaction with an alkyl phosphonate inhibitor.