Sentence examples for binding site as a from inspiring English sources
An experiment was performed using the 3F Zif268 peptide against its 9-bp binding site as a calibration reference, based on the fact that Zif268 binds with a Kd of approximately 2 nM (51).
Potential-invariant values of the constants for H2O2, H+ and O2 binding are determined and the rate constants for the reduction and the re-oxidation of the binding site as a function of potential are evaluated.
Potential- and temperature-invariant values of the constants for H2O2, H+ and O2 binding were determined and the rate constants for reduction and the re-oxidation of the binding site as a function of potential and temperature were evaluated together with the activation energy for the reduction of the binding site.
In our application of SRS to the domain of ligand-protein interactions, we consider a new parameter called escape time, the expected number of MC simulation steps required for the ligand to escape from the 'funnel of attraction' of the binding site, as a metric for analyzing such interactions.
To assess the involvement of FLNA in this acute opioid-induced Gs coupling, we co-treated slices with NLX, naltrexone (NTX), or FLNA2561 2565, their pentapeptide binding site, as a decoy for MOR.
The use of molecular modeling to delineate the structural basis for competitive inhibition of Stat3 SH2/pY-peptide binding by our compounds identified the hydrophobic binding site as a selectivity filter.
PPT1 is structurally similar to lipases and has a peptide binding site as well as a well-defined fatty acid binding pocket.
Other specific domains have also been described such as a PIP2 binding site as well as CAMKII and PKC phosphorisation site (Choi et al., 2014).
Our study revealed induced-fit adaptations within the mutated binding site as an essential prerequisite for ligand accommodation related to the selectivity discrimination of the ligands.
Since there is usually about one binding site per sequence, it is very likely that some agents may select a binding site as an initial solution.
Therefore, it is fairly intuitive to consider each DNA sequence as a bag, and any subsequence that can be a potential binding site as an instance.
