Sentence examples for binding site and was from inspiring English sources

A common insertion point lies close to the distal ubiquitin binding site and was proposed to include an autoinhibitory UBL domain in hUSP4.

SOX2 contains a putative HIF1 promotor binding site and was found to be strongly repressed after 3 d of exposure with WC-Co and CoCl2.

This variant was predicted to disrupt a SP1 consensus binding site and was shown to be associated with reduced gene expression.

Based on our previous experiences, we therefore concluded that further assessment of this panel of residues was unlikely to be fruitful in the search for a TAK-779 binding site and was not a good use of resources.

Most inhibitors are folate-analogs that bind at the folate binding site and are not species specific.

Using these models it is possible to design antagonists, which block the binding site and are thus species-specific insecticides.

The N-terminal part of FadB' comprises an NAD+ binding site and is responsible for 3-hydroxyacyl-CoA dehydrogenase activity converting (S -3-hydroxybutyryl-CoA to acetoacetyl-CoA.

The region of the protein responsible for binding another molecule is known as the binding site and is often a depression or "pocket" on the molecular surface.

Collectively, these results suggest that region DLC1 375–385 functions as a tensin2 PTB binding site and is required for tensin2 binding.

The gene might have oestrogen receptor binding sites and was highly expressed in the hippocampus region.

The hydroxylmethoxyphenyl group of 6 occupied back pocket I 15 of the ATP-binding site and was held in position by several polar interactions, including hydrogen bonds with the side chain of Lys42 in the kinase N lobe and Glu64 of helix C. In the absence of an inhibitor, the salt-bridge formed between these two residues typically stabilizes the DAPK1 active conformation.