Sentence examples for binding site and the from inspiring English sources

The structure implies that a single molecule of Smt3p cannot bind concurrently to both the non-covalent binding site and the catalytic cysteine of a single Ubc9p molecule.

NS3h contains two important binding sites: the NTPase binding site and the RNA binding site.

They present a pyridyl-thioether-based binding site and the anthracene moiety as a chromophore.

Mutation of flanking residues between the 3AB binding site and the polymerase active site specifically decreased 3B uridylylation, likely affecting steps subsequent to binding.

SAP 155's downstream cross-linking site is immediately adjacent to the U2AF binding site, and the two proteins interact directly in protein-protein interaction assays.

The left half of the panel depicts the UMI-4C with the following three primer viewpoints (indicated by the dotted line): the TSS, the p63 binding site, and the ATAC day 7 peak at the TFAP2C locus.

Previous studies have established the Cyclin A promoter to contain E2F-binding site and the promoter activity is repressed by the RB-E2F complex [24].

This evaluation revealed for the first time that ketoclomazone binds to the site of inhibition, which differs from both the pyruvate-binding site and the D-GAP-binding site on DXP synthase.

The kinetics of inhibition by ketoclomazone suggested that ketoclomazone binds to an unidentified inhibitor-binding site that differs from both the pyruvate-binding site and the D-GAP-binding site on DXP synthase.

The binding site of this enzyme possesses two main subpockets: the catalytic anion-binding site and the hydrophobic specificity pocket.

Gain-of-function mutations at several sites indicate the plastic nature of the ligand-binding site and the potential for natural polymorphisms to substantially alter ligand specificity and receptor activity.