Sentence examples for binding site and are from inspiring English sources

Most inhibitors are folate-analogs that bind at the folate binding site and are not species specific.

Using these models it is possible to design antagonists, which block the binding site and are thus species-specific insecticides.

Our observations provide an evidence for the preference of the anionic state (HD32D228) in BACE1 binding site and are in accord with reported computational data.

The pharmacophores are elucidated based on available crystal structures of bound ligands and/or simple examination of the binding site, and are used to filter the saved poses output from the docking program, and remove any that are incompatible with the model.

The side chains of the other substitutions do not point towards the binding site and are not expected to impact on hippuristanol affinity.

However, most of these methods focus on predicting interactions involving only a single binding site, and are not able to predict interactions involving multiple binding sites.

The N-terminal part of FadB' comprises an NAD+ binding site and is responsible for 3-hydroxyacyl-CoA dehydrogenase activity converting (S -3-hydroxybutyryl-CoA to acetoacetyl-CoA.

The region of the protein responsible for binding another molecule is known as the binding site and is often a depression or "pocket" on the molecular surface.

Collectively, these results suggest that region DLC1 375–385 functions as a tensin2 PTB binding site and is required for tensin2 binding.

SK binding sites are distributed in a pattern distinct from SP binding sites and are localized to the external circular muscle, external longitudinal muscle, and the muscularis mucosa.

ChIP primers were designed to span potential E4BP4 binding sites, and are displayed in Additional file 2: Figure S2.