Sentence examples for binding site and a from inspiring English sources

Each araC-pBAD promoter precedes a ribosomal binding site and a multicloning site (MCS).

The first step of the docking studies involves a detailed analysis of the binding site and a description of all aspects in relation to affinity and selectivity [18].

The conformational binding interface of BV is composed of two major areas, a β-Gal binding site and a Le epitope binding site, formed by ten amino acids from 3 (P-, T-, and S-) loop regions (Fig. 5).

This revised procedure differs from the P-ER1 protocol to design molecular PASS gates presented in [30] by adding another effector binding site and a linker in the extension region of helix II.

The second folded region contained a highly protected PKA binding site and a more solvent-accessible PDZ binding motif, which may serve as a potential targeting domain for D-AKAP2.

FCIA is based on the hypothesis that an appropriately designed stilbene-antigen analogue probe will suffer considerable steric hindrance to trans-cis photoisomerization when bound within the combined constraints of both an antibody binding site and a second globular protein.

What's more, the ATP-binding site and A-loop motif had been identified to play key roles in TYK2-targeted inhibitor discovery.

Middle: conserved residues (magenta) surround the AdoMet-binding site and a conserved Cys could bind a Fe4S cluster.

Synthetic molecules bind Ras in a region belonging to the more extended Ras/GEF-binding site, and a possible mechanism of Ras inhibition by these compounds can be the blockade of GEF-mediated nucleotide exchange.

Thus, this pocket is a promiscuous drug-binding site and a likely target for different assembly effectors with a broad range of mechanisms of activity.

To minimize such side effects, we have designed an epidermal growth factor receptor (EGFR -specific maskEGFR -specific which consists of a maskedg peptide that bloCAR the antigen-binding site and a protease-sensitive linker.