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Of the nine ICAM-1 binding signatures defined by this approach, only the "ca" type was more frequent among the severe malaria isolates than among the UM isolates, but this was not statistically significant (Odds Ratio 7.750 (95%CI 0.896 67.02) p = 0.056, two-tailed Fishers exact).
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We found that a high-risk signature defined by infiltration of inflammatory and immune cells was an independent predictor of poor prognosis in ECC patients with surgical resection.
The expression values of "500 gene signature," defined by the authors, were extracted from the data.
To this end, we calculated for each sample the difference between mean expression of the mesenchymal signature and the epithelial signature defined by Loboda and colleagues.
In this first follow-up evaluation, we decided to focus on the prognostic signature defined by TRAF2, SHKBP1 and UBC.
(g) All CpGs in both proliferating and arrested ESCs that overlap with OCT4 binding sites (defined by ChIP-seq, ENCODE H1 human ESCs) are displayed.
Non-specific binding was defined by 1 µM NTX.
Nonspecific binding was defined by unlabeled 100 μM β-NAD+.
Non-specific binding was defined by unlabelled ZM241385 (1 μM).
Given two statistical signatures, and, a novel dissimilarity measure between two statistical signatures is defined by (4).
These molecular signatures are defined by the genes and pathways described above.
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CEO of Professional Science Editing for Scientists @ prosciediting.com