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As shown in Figure 2A, scatter plots of the H-NS binding signals in both strains showed a genome-wide positive correlation (correlation coefficient = 0.91).
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It enhances the binding affinity to HA and shows high binding signals in the sensorgrams.
Second, binding signals in the ChIP-chip data do not necessarily imply functionality.
Second, binding signals in the ChIP data do not necessarily imply functionality.
We compared PolII binding signals in MCF7 before and after 4 hour E2 stimulation.
The other six proteins showed weak binding signals in our competition assay, presumably due to the reasons discussed above.
In contrast to the 77% for binary-only DPs, only 40% of the cap-only DPs had stronger binding signals in G1E than in ER4.
Modifications made to the B. subtilis SSB probe allow us to attain high resolution ssDNA binding signals in complex multi-protein assays with high tryptophan backgrounds.
When pre-defined binding regions are available for directly testing differential binding, X j became a N by P data matrix containing the binding signals in all binding regions in condition j.
ChIP/chip experiments showed distinct AHR binding signals in naive and ligand-exposed wild-type Hepa-1c1c7 cells but no signal in the mutant c35 cells, indicating that the signal was entirely AHR dependent.
Crm1 binding signals in control, Nup98-HoxA9 ES cells, and TSA-treated Nup98-HoxA9 ES cells were mapped against either Crm1 (bottom, left) or FLAG-Nup98-HoxA9 binding sites (bottom, right) of untreated cells.
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